Endocrine Abstracts

Familial hypoparathyroidism is a rare condition. A family with seven affected individuals is described. Six sets of case notes were available for comparison. The most probable type of genetic transmission is autosomal dominant. There is also a family history of renal stones and ankylosing spondylitis.At diagnosis, adjusted calcium levels ranged between 1.77 and 1.92 mmol/L. PTH levels were either undetectable or in the low-normal range. Most cases were s...

Hyperemesis gravidarum is vomiting in pregnancy severe enough to cause weight loss and hospitalization. It occurs in up to 1% of pregnancies. It usually begins at 6–9 weeks gestation and resolves by 18–20 weeks. It can lead to dehydration and electrolyte imbalances. Treatment includes intravenous fluids and anti-emetics. The cause of vomiting is unknown. Hyperemesis gravidarum is often associated with transient gestational hyperthyroidism.The a...